Friday, 30 November 2012
Autogenics - the Yin of Hormesis
Autogenics is one of the best methods to relax totally, in mind and body. With practise you can rapidly achieve a state of warmth and total relaxation, with a cool forehead and calm, detached mind as the objective.
I've been practising it for 25 years and find it very helpful every morning, after a work-out.
You don't need a teacher - just find a good book or material on-line and then practise every day, ideally twice a day.
Wednesday, 14 September 2011
Hormesis, cell death and aging
Hormesis, cell death and aging
- Isabelle Martins, Lorenzo Galluzzi and Guido Kroemer
Abstract
Frequently, low doses of toxins and other stressors not only are harmless but also activate an adaptive stress response that raise the resistance of the organism against high doses of the same agent. This phenomenon, which is known as "hormesis", is best represented by ischemic preconditioning, the situation in which short ischemic episodes protect the brain and the heart against prolonged shortage of oxygen and nutrients. Many molecules that cause cell death also elicit autophagy, a cytoprotective mechanism relying on the digestion of potentially harmful intracellular structures, notably mitochondria. When high doses of these agents are employed, cells undergo mitochondrial outer membrane permeabilization and die. In contrast, low doses of such cytotoxic agents can activate hormesis in several paradigms, and this may explain the lifespan-prolonging potential of autophagy inducers including resveratrol and caloric restriction.
Thursday, 3 March 2011
Paleo Diet
From http://www.paleonu.com/panu-weblog/2009/11/13/what-i-eat.html
>> I don't count, weigh or measure and I only look up the contents of what I am eating for research purposes (curiosity or the blog).
I eat about 5 % of calories as carbohydrate right now. Partly that is because I seem to be somewhat starch intolerant and I see little point in adding things like potatoes and rice that I didn't eat much before. It is not because I am specifically following Kwasneiwski's optimal diet, it just works out that way. But many of my own premises lead the same direction as Kwasniewski, so that's just confirmation in my mind. I suspect anything from 0-30% carbs will work fine (for health) for most people. If you want to go beyond that to Kitavan levels with Yams or white rice, I doubt if that is as healthy, but that might be OK, too if you have extirpated the neolithic agents.
My staples are:
Grass fed beef and lamb, wild venison (whitetail deer), bison. I eat the hearts and livers, don't care for the kidneys. Codfish, wild salmon and trout from lake michigan, sashimi (maguro especially). Wild turkey (the bird not the liquor)
Eggs - pastured eggs averaging 4 a day - often garnished with green or red chili salsa and sour cream. Onions and mushrooms for accompaniment.
Whole cream - in coffee and straight up. Diesel #1.
Pastured butter - I use it to cook everything and add it to stews and chili. Diesel #2.
Bacon, smoked bacon and prosciutto ham maybe once a week. (Penn Jillette says bacon is the perfect food)
Occasional sardines in olive oil or water.
Cheeses - Gorgonzola, parmesan, cheddar, brie, etc.
Veggies mostly as condiments - Red, yellow and white onions, regular and portabella mushrooms, wild morels and chantarelles in season, asparagus, green beans, different varieties of chilis.
Our main fruit is tomatoes eaten whole or crushed in tomato sauce for stew or chili. Lots of avocado with breakfast. A handful of raspberries and occasionally blueberries topped with unsweetened whole whipped cream now and then. Add vanilla to the whipped cream.
"Nuts" - limited pecans, almonds and walnuts - not for health just for flavor.
Any day we eat factory meat or get a big dose of n-6 PUFAs in restaurant food (Mcdonald's burger without bun, barbecued store bought chicken, restaurant eggs fried in vegetable oil) we each take 1 teaspoon of Carlson's cod liver oil.
You know about the vitamin D - now 8000 units/day Carlson's drops in morning coffee.
Sunday, 5 December 2010
Hormesis: COLD
From Own Your Health - http://is.gd/ieMRi
Cold Showers: What’s the Evidence?
Some people have questioned the evidence behind hydrotherapy, especially the cold water treatments that are described in the book that Alexa Fleckenstein and I co-authored. German research supports the effects of cold water used on the skin as therapy. Unfortunately, the studies are in German, and they are small. (1) Because Pharma firms have no interest in inexpensive water cures, there probably won’t be big studies any time soon. Fact is, the German insurance system pays all or part of physician-prescribed treatments, including hydrotherapy and herbs. The importance and therapeutic potential of water, and especially cold water, are now simply taken for granted in Germany.(2) Here are some specific research studies supporting the health benefits of cold water treatments. Citations are listed at the end. (More cold water research details in Own Your Health (2003)
Boosting the immune system
A pilot study of immune effects from cold water therapy with a small number of breast cancer patients found significantly increased disease-fighting cell counts in every category examined, including neutrophils, lymphocytes, monocytes.(3)
Reducing the perception of pain
In a study in Japan, cooling by ice water was one of the “competitive stimuli” that reduced the perception of the pain of a laser beam on the skin. (4)
Improved circulation and function in the legs
A Swedish group administered three weeks of alternating cold and hot hydrotherapy to the legs of patients suffering from intermittent claudication (reduced blood flow) and found that improved systolic blood pressure in ankles and toes, reduced pain, and markedly better walking ability went beyond the results of standard treatment and persisted for at least a year after treatment.(5)
Swimming in the winter?
Ten healthy subjects who regularly swim during the winter were evaluated at Berlin’s Institute of Biochemistry at Humboldt University Medical School. Their blood and urine showed increased levels of anti-oxidants, which prevent cell damage, indicating their bodies’ increased tolerance to stress.(6)
(1)Summarized in Bühring, M., Naturheilkunde: Grundlagen, Anwendungen, Ziele (Natural Medicine: Basic Application and Goals), Munich, Verlag CH Beck, 1997.
(2)Haas, S.S., Hydrotherapy and more: Adapting Kneipp’s Natural Medicine to the U.S., Complementary Medicine for the Physician, 2000; 5(8):57,61-64.
(3)Kuehn, G., Sequential hydrotherapy improves the immune response of cancer patients. In: Mizrahi A, et al., (eds.) Potentiating Health and the Crisis of the Immune System: Integrative Approaches in the Prevention and Treatment of Modern Diseases. New York: Plenum, 1997.
(4)Kakigi R., et al. Pain relief by various kinds of interference stimulation applied to the peripheral skin in humans: pain-related brain potentials following CO2 laser stimulation. J peripher Nerv Syst 1996;1:189-198.
(5)Elmstahl, S. et al., Hydrotherapy of patients with intermittent cluadication: a novel approach to improve systolic ankle pressure and reduce symptoms. Int Angiol. 1995;14:389-394.
(6) Siems, W.G., et al., Uric acid and glutatione levels during short-term whole body cold exposure. Free Radic Biol Med. 1994;16:299-305.
Take a Cold Shower to Protect Against Colds and Flu This Winter
At first, it sounds crazy – can a cold shower really prevent colds and flu? But Dr. Alexa Fleckenstein, author of HEALTH 2 0: TAP INTO THE HEALING POWERS OF WATER TO FIGHT DISEASE, LOOK YOUNGER, AND FEEL YOUR BEST (McGraw-Hill 2007) says that a few seconds of cold water after your hot shower is scientifically proven to make you healthy – even if you’re in the cold water for less than 30 seconds a day.
Here are 6 ways that a short cold shower protects you from colds and flu:
1. A brief cold water shower will decrease your body’s “reaction time” to cold. The cold shower “teaches” the blood vessels in your skin to clamp down faster, so you are losing less warmth in draft or cold exposure. Especially, during the winter months while it’s cold outside, you’ll stay warmer, longer.
2. Gamma interferon and interleukin-4 are two important virus-fighting cytokines (immune system proteins) A new German study has shown that cold water exposure helps these two disease-fighters work better together, resulting in fewer viral colds.
3. A cold shower increases lymphocytes in the blood. Lymphocytes produce antibodies, which help fight germs.
4. A cold shower makes you breathe deeply. (A big gasp when the cold water hits the skin!) A deep breath opens closed or clogged alveoli (small air sacs in the lungs) which are then less prone to bronchitis and pneumonia. And deeper breathing means more oxygen for the whole body.
5. A cold shower increases blood flow in all organs, especially skin, heart and lungs. The pharynx/larynx ( organs of the throat) also benefit from the increased blood flow, and are better able to kill viruses.
6. And a cold shower lifts your mood. Depressed people get more colds – probably because depression lowers immunity. A brisk cold shower has been proven to lift the mood and lower stress, both of which jumpstart the immune response – which kills flu and cold germs!
Remember that cold water therapy works only if done regularly, and also needs a few weeks (about six) to work. Start with just your feet and hands in the cold water, and gradually work your way up to your whole body. It feels great!
IMPORTANT: Check with your doctor first. Contraindication include uncontrolled high blood pressure, and narrowing of the arteries.
Sunday, 14 November 2010
anti-agingfirewalls.com
Getting Stronger
http://gettingstronger.org/hormesis/
Sunday, 21 March 2010
Does caloric restriction increase longevity?
Greg Critser (new book is Eternity Soup: Inside The Quest To End Aging,Harmony 2010):-
"Hormesis theory — the notion that caloric restriction (the only intervention that expands maximum lifespan in mammals — mice) works by putting the body in a kind of energy-saving hibernation state, is promising. But the pathway by which it seems to work—ratcheted down Insulin-like Growth Factor 1 (IGF-1), does not seem implicated in exceptional human longevity; in one recent study only 6 of 220 human centenarians had the mutated IGF -1 receptor. Also, human beings do very badly on low IGF 1. They get sick and die". See
http://www.scientificblogging.com