Friday 11 September 2009

Welcome to Hormesis Health

From Dr. B G Animal Pharm
http://drbganimalpharm.blogspot.com/2009/05/become-b-i-o-n-i-c.html

A researcher in Denmark, Dr. S. Rattan, has written about the benefits in extending lifespan via hormesis (Ageing Res Rev. 2008 Jan;7(1):63-78). "Hormesis in aging is represented by mild stress-induced stimulation of protective mechanisms in cells and organisms resulting in biologically beneficial effects. Single or multiple exposure to low doses of otherwise harmful agents, such as irradiation, food limitation, heat stress, hypergravity, reactive oxygen species and other free radicals have a variety of anti-aging and longevity-extending hormetic effects. (me thinks the torture umm... the WODs at X-fit fit this definition) Detailed molecular mechanisms that bring about the hormetic effects are being increasingly understood, and comprise a cascade of stress response and other pathways of maintenance and repair. Although the extent of immediate hormetic effects after exposure to a particular stress may only be moderate, the chain of events following initial hormesis leads to biologically amplified effects that are much larger, synergistic and pleiotropic. A consequence of hormetic amplification is an increase in the homeodynamic space of a living system in terms of increased defence capacity and reduced load of damaged macromolecules. Hormetic strengthening of the homeodynamic space provides wider margins for metabolic fluctuation, stress tolerance, adaptation and survival. Hormesis thus counter-balances the progressive shrinkage of the homeodynamic space, which is the ultimate cause of aging, diseases and death. Healthy aging may be achieved by hormesis through mild and periodic, but not severe or chronic, physical and mental challenges..."


Brief cold stress appears to improve our immune systems by stimulating the hypothalamic-pituitary-adrenal and hypothalamic-pituitary-thyroid axes as described HERE research is reviewed including an experiment where T. gondii-infected-rats had improved survival with cold-hydrotherapy x8days.

Exposure to periodic, repeated, short term (like 2-7mins) cold stress induces hormesis which can help to rebuild and regenerate our bodies and minds... making us... stronger, better, more powerful...

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